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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC2
All Species:
45.15
Human Site:
T323
Identified Species:
70.95
UniProt:
P35250
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35250
NP_002905.2
354
39157
T323
F
I
K
E
I
G
Y
T
H
M
K
I
A
E
G
Chimpanzee
Pan troglodytes
XP_001149874
354
39149
T323
F
I
K
E
I
G
Y
T
H
M
K
I
A
E
G
Rhesus Macaque
Macaca mulatta
XP_001082511
352
38844
T321
F
I
K
E
I
G
Y
T
H
M
K
I
A
E
G
Dog
Lupus familis
XP_546916
352
38707
T321
F
I
K
E
I
G
Y
T
H
M
K
I
A
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUK4
349
38706
T318
F
I
K
E
I
G
Y
T
H
M
K
V
A
E
G
Rat
Rattus norvegicus
Q641W4
349
38638
T318
F
I
K
E
I
G
Y
T
H
M
K
V
A
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516769
407
45006
T376
F
I
K
E
I
G
Y
T
H
M
K
V
A
E
G
Chicken
Gallus gallus
P53033
359
39688
T328
F
I
K
E
I
G
Y
T
H
M
K
I
A
E
G
Frog
Xenopus laevis
NP_001084837
348
38438
T318
F
I
K
E
I
G
Y
T
H
M
K
I
A
E
G
Zebra Danio
Brachydanio rerio
NP_001013344
349
39005
T318
Y
I
K
E
I
G
Y
T
H
M
K
V
A
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53034
331
37155
I300
K
L
D
F
I
R
E
I
G
I
T
H
M
K
I
Honey Bee
Apis mellifera
XP_623937
350
39000
I320
K
L
D
F
V
K
E
I
G
I
T
H
L
G
I
Nematode Worm
Caenorhab. elegans
P34429
368
41157
V326
I
I
T
G
L
G
E
V
E
E
N
L
S
T
G
Sea Urchin
Strong. purpuratus
XP_790650
352
38724
T320
F
I
K
E
I
G
M
T
H
M
R
I
A
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40339
323
36131
V280
V
T
K
N
L
A
Q
V
K
E
S
V
R
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
93.5
N.A.
92.3
91.5
N.A.
76.6
87.7
86.4
82.7
N.A.
68.9
67.2
35
71.1
Protein Similarity:
100
99.7
98.8
96.6
N.A.
95.4
94.9
N.A.
81.5
91.6
91.5
88.4
N.A.
79.6
78.8
51.6
85.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
100
100
86.6
N.A.
6.6
0
20
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
26.6
20
40
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
0
74
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
74
0
0
20
0
7
14
0
0
0
74
7
% E
% Phe:
67
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
80
0
0
14
0
0
0
0
7
80
% G
% His:
0
0
0
0
0
0
0
0
74
0
0
14
0
0
0
% H
% Ile:
7
80
0
0
80
0
0
14
0
14
0
47
0
0
14
% I
% Lys:
14
0
80
0
0
7
0
0
7
0
67
0
0
7
0
% K
% Leu:
0
14
0
0
14
0
0
0
0
0
0
7
7
7
0
% L
% Met:
0
0
0
0
0
0
7
0
0
74
0
0
7
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
7
0
7
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% S
% Thr:
0
7
7
0
0
0
0
74
0
0
14
0
0
7
0
% T
% Val:
7
0
0
0
7
0
0
14
0
0
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _